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The Next Stent Frontier: Nanotechnology

This article was originally published in Start Up

Executive Summary

The medical device world is buzzing these days in anticipation of the early clinical success of drug-eluting stents in preventing restenosis, but it's never too soon to look toward the next generation of innovation. One of the next big steps on the stent horizon will be nanotechnology, according to interventional cardiologist Steven Bailey, MD.

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World Congress of Cardiology: DES Safety Dominates Discussions

While the greater efficacy of drug-eluting stents (DES) compared to bare-metal stents is widely accepted, over the past year, data has continued to build showing that first-generation DES also have a higher late-stage in-stent thrombosis risk, a complication that can cause death 30% of the time, according to some estimates. The findings of these studies had some physicians at this year's World Congress of Cardiology calling for "an immediate halt to DES overuse." However, most conceded that additional randomized trials will be needed to fully understand the potential risks associated with these devices.

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