NEJM Report: Next-Gen Gene Sequencing Solves Difficult Rare Infection Case
This article was originally published in The Gray Sheet
Executive Summary
Clinicians used unbiased next-generation gene sequencing of cerebrospinal fluid in a boy with severe immunodeficiency to discover he was infected with a rare bacterial pathogen. The case, published in the New England Journal of Medicine, suggests next-generation sequencing may help doctors treat patients with diseases that cannot be identified through conventional testing, researchers say.