Down’s Syndrome

First-semester combination screening is better than second-semester quadruple screening for identifying fetal Down's Syndrome, according to the results of the 38,167 patient FASTER trial, published in the Nov. 10 New England Journal of Medicine by Fergal Malone, MD, Columbia University, et al. "When there is an appropriate quality control for measurement of nuchal translucency [the space in the tissue at the back of the fetus' developing neck], first-trimester combined screening is a powerful tool for the detection of Down's Syndrome," the authors conclude...