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Start-Up News March 2008

Executive Summary

Noteworthy news from medtech start-ups, including Angel Medical's implantable early warning system for heart attacks and Innovent Medical's non-invasive device to prevent ventilator-associated pneumonia in the ICU.

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Hospital-Acquired Conditions: Patient Safety Concerns Fuel Device Innovation

New federal initiatives to improve patient safety are taking direct aim at hospitals' bottom line by making them bear the increased costs of treatment when patients acquire a condition deemed reasonably preventable. At this year's meeting of the Association of Operating Room Nurses, companies showcased new technologies designed to help hospitals avoid so-called "never events" like leaving objects in a patient after surgery, pressure ulcers acquired during a patient's stay, and certain nosocomial infections.

Innovent Medical Solutions Ltd.

Ventilator associated pneumonia (VAP), the second most common infection in the ICU, is caused when infected secretions that accumulate in and around the endotracheal tube leak into the lungs. Innovent Medical Solutions Ltd. intends to reduce both the incidence and the cost of treating VAP with noninvasive technology that mimics nature's own method for clearing airways: the cough. T In addition to decreasing the number of VAP cases by 50%, the company thinks its technology will also facilitate more use of noninvasive facemask ventilation, leading to an improvement in the quality of life for ICU patients.

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