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Bifurcation Stenting: The Next Generation

This article was originally published in Start Up

Executive Summary

The proper course of action for treating lesions at bifurcations remains controversial. In the face of numerous small studies with conflicting results and in the absence of large-scale studies investigating whether--or how--to stent the side branch of a bifurcation, cardiologists are searching for solutions. It's all very confusing, but one thing is becoming increasingly clear. Drug-eluting stents, which work so well in straight segments of vessels, aren't working in bifurcated vessels because bifurcations are distinct segments of anatomy, with particular shapes and unique flow characteristics. Start-ups have picked up on the fact that there is a $1 billion interventional cardiology market just waiting to be served with the right technology, and almost a dozen young companies have crowded into the field.

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Cappella: Can a New Twist On An Old Idea Solve the Bifurcation Challenge?

Device companies large and small have failed repeatedly in efforts to address bifurcations, which remain one of the largest unmet opportunities in cardiology. Cappella thinks it can solve the problem with a device that's a new version of an old idea, reversing current protocol to treat the side branch first.

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