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What's All the Flap About PFO Closure?

This article was originally published in Start Up

Executive Summary

A congenital heart defect known as a patent foramen ovale or PFO is a newly recognized risk factor for stroke, and surprisingly, migraine. NMT has an approved interventional cardiology device that's ready to serve, but the opportunity is still undefined. Neurologists and the FDA are waiting to see the results of randomized, clinical trials with appropriate follow-up, which, they hope, will address several unanswered questions in the field, including the most fundamental: what is the link between a PFO and the risk of stroke?

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