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Computed tomography (CT) expands its role in cancer

This article was originally published in Clinica

Executive Summary

CT guidance can increase the success of gene therapy for cancer, said Professor Evan Unger, director of cross-sectional imaging at the University of Arizona, Tucson, at RSNA in Chicago (November 26th-December 1st). Prof Unger's team used CT guidance to inject the common human lymphocyte antigen gene HLA-B7 into metastatic melanoma tumours in patients lacking the gene. "The theory is, when HLA-B7 is expressed on the surface of the cancer cells, the body's natural immune system mounts a defence to destroy them. CT allowed us to target the living cancer cells to maximise uptake," said Prof Unger.

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