Medtech Insight is part of the Business Intelligence Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

Replicative senescence in atherosclerosis:

This article was originally published in Clinica

Executive Summary

The cell ageing process - replicative senescence - may play an important role in the development of clinical vascular disease, as an accumulation of senescent endothelial cells in the arteries contributes to atherosclerotic plaque formation and thrombosis. These conclusions (Proceedings of the National Academy of Sciences, November 21st), by a team from Geron (US), were drawn following the observation that chromosomal telomere length can be used as a marker of human vascular ageing, and telomere loss in vivo is greater in cells from tissues implicated in atherosclerosis (eg arteries), than in cells not involved (eg from veins).

Advertisement

Topics

Advertisement
UsernamePublicRestriction

Register

MT094369

Ask The Analyst

Please Note: You can also Click below Link for Ask the Analyst
Ask The Analyst

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel