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Urine marker beats triple serum test for Down's detection

This article was originally published in Clinica

Executive Summary

A urine marker used for ovarian cancer detection is a more powerful predictor of Down's syndrome than the combined triple serum test and could also be cheaper. The discovery that urinary gonadotropin fragment (UGP) can detect 80% of Down's syndrome pregnancies was first made by Professor Howard Cuckle, at Leeds General Infirmary (UK) in 1994 and has now been confirmed in a US study.





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