Endometriosis linked to infertility:
This article was originally published in Clinica
Two cell adhesion molecules, alphav-beta3 and leukaemia inhibitory factor, may identify which women with endometriosis will have difficulty conceiving, according to US research at the University of North Carolina at Chapel Hill. In the July 1 issue of Fertility and Sterility, Bruce Lessey and colleagues report that injection of peritoneal fluid from infertile women with endometriosis into recently mated female mice resulted in a decreased implantation rate. Both adhesion molecules were deficient or absent from the peritoneal fluid. The researchers said that they believe the molecules are markers of uterine receptivity and that their absence could identify women with endometriosis who might benefit from medical or surgical treatment.