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New Alzheimer's marker discovered:

This article was originally published in Clinica

Executive Summary

The combination of the APOE E4 gene and a previously unknown gene in a small area of chromosome 10 is associated with a 16-fold increase in the risk of developing Alzheimer's disease among first-degree relatives of known cases of the disease, researchers at the University of Pittsburgh, Pennsylvania, have found. Reporting the finding in the June issue of Molecular Psychiatry, Dr George Zubenko and colleagues say that the gene may help identify those patients most likely to respond to therapy. The risk locus also affects brain levels of dopamine, and may be implicated in Parkinson's disease.

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