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Cryoseal fibrin sealant shows promise in TKA (total knee arthroplasty):

This article was originally published in Clinica

Executive Summary

ThermoGenesis says that an early study has produced evidence to support the use of its CryoSeal autologous fibrin sealant in total knee arthroplasty (TKA). The 21-patient pilot trial showed that total blood loss in TKA was reduced by 50% when using the sealant. The CryoSeal patients also had better cardiovascular stability, a higher range of motion, less pain and better wound healing than the control group. Plans are underway to confirm the results in a larger study. It has been estimated that over 1.3 million TKA procedures are performed annually worldwide, says the Rancho Cordova, California firm. The CryoSeal FS system is CE-marked for sale in Europe.

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