Researchers identify tumour gene:
This article was originally published in Clinica
Executive Summary
Italian scientists have identified a cancer gene that they say is present in around 74% of tumours. The Trop-2 gene was found to be expressed in the vast majority of cancers, including breast, colon, stomach, lung, prostate, ovary, endometrium, uterine, cervix and pancreas, claimed the researchers, based at the University of Chieti Foundation. In contrast, the gene p53, the most fundamental of tumour suppressors, is indicated in just 50% of tumours, and most other markers can only be detected at high frequency in a subgroup of tumours, said the team. Trop-2 may also play a major role in the spread of cancer. The team's findings were presented at the conference of the European CanCer Organisation (ECCO) in Barcelona, Spain, from 23-27 September.
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