Multiple sclerosis marker identified:
This article was originally published in Clinica
A new marker for multiple sclerosis (MS) has been identified by an Italian-German research team. The protein marker, CD39, is thought to completely disappear in patients with the disease. CD39 is found on the surface of a subgroup of protective immune cells - suppressor cells - which are strikingly reduced in MS patients. In normal individuals, CD39 is thought to curb inflammation in the central nervous system during the course of the disease. The research team, based at the Fondazione Santa Lucia, in Rome, Italy, and the Max Delbruck Center for Molecular Medicine, in Berlin-Buch, Germany, hopes that the future will show whether the marker will become clinically useful. The findings appear in the August 15 issue of Blood.
You may also be interested in...
FDA action awaits Sun’s manufacturing facility in Halol after it failed to adequately address GMP deviations, though India’s top-ranked drug firm appears to have effectively lowered its dependence on the site that has had a patchy compliance run.
In a surprise to the market, Dr Reddy’s and Hikma have prevailed in challenging six method-of-use patents shielding Amarin’s Vascepa in the US, opening the door for a potential at-risk launch that would likely be challenged by the originator.
Duo will study up to four novel preclinical targets identified by Sitryx that may lead to potential new drugs for autoimmune diseases, which Lilly would then commercialize.