Scientists link anti-inflammatory protein gene to IBD
This article was originally published in Clinica
Ulcerative colitis, a form of inflammatory bowel disease (IBD), could be caused by defective interleukin (IL)-10 function, research suggests. A genome-wide association study in 1,167 people with the disorder and 777 healthy controls found that a single nucleotide polymorphism close to the IL-10 gene was more common in the patients. IL-10 is an anti-inflammatory cytokine that has previously been linked with IBD, and treatment with IL-10 has shown promise in early studies. Previous studies on susceptibility genes for IBD have focused on Crohn's disease, another IBD subtype; however, the association between the variant and Crohn's disease was found to be weak. The results were published online in Nature Genetics on October 5.
You may also be interested in...
Israel is well-known as a medtech hot-spot, with a focus on academic research and strong government support helping the country punch well above its weight when it comes to innovative devices.
St Jude Medical had a heavy focus on its intravascular imaging offering at this year’s EuroPCR meeting, presenting data supporting its optical coherence tomography (OCT) technology. OCT provides intravascular images to help assess culprit lesions, which can improve stent selection and deployment, according to St Jude.
A big topic at this year’s EuroPCR, held in Paris on 19-22 May, was drug-coated balloons (DCBs). One of the leaders in the field, Medtronic, presented positive data from two studies of its IN.PACT Admiral balloon, which could support an expanded indication for the device.