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Mesynthes Ltd.

This article was originally published in Start Up

Executive Summary

Mesynthes Ltd.'s soft tissue regeneration and reconstruction platform, based on a proprietary extracellular matrix derived from the sheep forestomach, provides a biological template for tissue repair. Animal studies have demonstrated that the architecture of the matrix--including the vascular channels and the structural, fibrillar, and adhesive proteins, such as collagen and elastin--supports the ingress and growth of keratinocytes, fibroblasts, and mesenchymal and inflammatory cells. The extracellular matrix also releases important biological macromolecules that trigger tissue regeneration.

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