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Orthopedic Soft Tissue Repair

This article was originally published in Start Up

Executive Summary

Each year more than 1.6 million patients undergo surgeries for the repair of tendons, ligaments and cartilage in the shoulder, knee and ankles. The lack of efficacy of some of past offerings in soft tissue repair has created a pent-up demand for new treatment tools.

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Tissue Repair Start-Ups Fill Orthopedics' Gaps

Technologies for total joint repair, the backbone of the orthopedics industry, have occupied most of the development resources of orthopedic companies, but there are gaps in the continuum of care when it comes to tendon and ligament repair. ACL reconstruction and rotator cuff repair thus are attractive niches for start-ups, worth anywhere from $500 million to $1 billion. Soft tissue repair expertise is outside the core skill-sets of big ortho, but those companies have been willing to partner and acquire smaller innovative players. Today, the opportunity is even more attractive; sports medicine--the realm of soft tissue repair--enjoys an economic resiliency not seen in total joint replacement. Ligament tears more closely resemble trauma applications, which must be treated as soon as possible.

Healionics Corp.

Device manufacturers looking to bolster the biocompatibility of their products can now turn to Healionics, a supplier of biomaterial scaffolds designed to improve the biointegration of percutaneous or fully implanted medical devices. The company's STAR technology is a synthetic, three-dimensional matrix, similar to a thin, porous sponge. Because this biomaterial has been precisely engineered with uniform pore sizes to the approximate size of a single cell, the company says that living tissue and new blood vessels actually grow and weave into these pores.

Closing the Gap in Ventral Hernia Repair

Most complex ventral, or incisional, hernias are managed by open surgical techniques, and the choice of prosthetic mesh used in these procedures has become a hot issue. With prices upwards of $10,000 per patient for patch materials, it is no surprise that all eyes are on the ventral hernia patch market.

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