Medtech Insight is part of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC’s registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By

UsernamePublicRestriction
UsernamePublicRestriction

Research News In Brief

This article was originally published in The Gray Sheet

Executive Summary

Ablation SMASHes VT: Substrate-based catheter ablation reduces defibrillator shocks in patients with an ICD and a history of myocardial infarction, according to results of the 128-patient SMASH-VT trial, published in the Dec. 27 New England Journal of Medicine. The National Institutes of Health-supported trial randomized patients with a previous heart attack and spontaneous ventricular tachycardia or fibrillation to be treated with an ICD alone or an ICD plus catheter ablation. The primary endpoint was survival with no ICD shocks or pacing needed to treat an arrhythmia. Mean follow-up was 22.5 months. 31% of the patients in the ICD-only group received an appropriate shock compared with 9% of the ICD-plus-ablation group. Mortality was statistically similar for both groups - 17% for the control and 9% for the ablation group. Lead author Vivek Reddy, M.D., Massachusetts General Hospital, says the study results should be confirmed in larger studies that also analyze the impact of antiarrhythmic drugs. "In addition, a formal economic analysis would be needed to adequately understand the relationship between the immediate costs of the ablation procedure and the long-term costs of care for patients with ICDs," Reddy explains
Advertisement

Related Content

Advertisement
UsernamePublicRestriction

Register

MT025637

Ask The Analyst

Please Note: You can also Click below Link for Ask the Analyst
Ask The Analyst

Your question has been successfully sent to the email address below and we will get back as soon as possible. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts

Cancel