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Drug-Eluting Stent Wars Reach Standoff In Diabetic Patients

This article was originally published in The Gray Sheet

Executive Summary

The largest comparison to date of paclitaxel-versus sirolimus-eluting stents in diabetic patients failed to show a statistically significant difference in outcomes between the two devices, according to findings unveiled March 12 at the American College of Cardiology's annual meeting in Atlanta

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...and diabetes patients

Boston Scientific claims superior two-year results for Taxus compared to Cypher and bare-metal stents in a population of patients with diabetes, based on 708-patient registry data reported at the AHA Scientific Sessions Nov. 14. In the European T-Search/Research study, the target vessel revascularization rate was 9.7% for Taxus compared with 15.3% for Cypher and 19.5% for bare-metal stents. MACE (major adverse cardiac event) rates were 21.2% with Taxus, 28.9% with Cypher and 29.7% with bare-metal stents. Data from 1,182 diabetic patients in another Boston Scientific-sponsored registry reported earlier this year showed no statistically significant difference between the two drug-eluting products (1"The Gray Sheet" March 20, 2006, p. 4). Diabetics make up 25% of patients receiving coronary interventional procedures in the U.S., Boston Scientific says...

Who’s Hired? Hikma Recruits New US Generics President

A flurry of top level recruitments made headlines in the past weeks, with the likes of Hikma, Lupin, and Viatris announcing new hires while focusing on their targets for the year.

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